I7663-25K8

Interleukin 1 Receptor Type II (IL-1RII, IL1R2, IL-1R2, IL-1R-2, IL-1RT2, IL-1RT-2, CD121 Antigen-like Family Member B, CD121b, CDw121B, Interleukin-1 Receptor beta, IL-1R beta, IL-1R-beta, IL1RB, IL1-Rb, MGC47725) (APC)

Size

£843.00

SKU:: I7663-25K8
Application:: Flow Cytometry
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: 4°C Do Not Freeze
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Purified, recombinant protein corresponding to aa14-343 of human IL-1R II, expressed in Sf 21 insect cell line.
Clone:: 11C25
Format:: Supplied as a liquid in saline, <0.5% BSA, 0.09% sodium azide. Labeled with Allophycocyanin (APC).
Extra Details:: Interleukin-1 receptor II (IL-1 RII), also known as CD121b, is an immunoglobulin superfamily receptor that binds the pleiotropic cytokines IL-1a and IL-1b. It acts as an IL-1 antagonist because it has a short cytoplasmic domain and does not transduce IL-1 signals. IL-1 RII exists both as a transmembrane protein and as a soluble form that is released by proteolysis. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 10ul/10e6 cells using human peripheral blood mononuclear cells Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.