I7662-89Q
Interferon Regulatory Factor 6 (IRF6)
Size
£642.00
- SKU:
- I7662-89Q
- Purity:
- Purified by peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Goat
- Immunogen:
- Synthetic peptide corresponding to C-TPSMQLPPALPPQ, from the C Terminus of human IRF6 (NP_006138.1).
- Format:
- Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
- Extra Details:
- This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications have not been tested. Recommended Dilutions: Peptide ELISA Titer: 1:1:32,000 Immunohistochemistry: 2-3ug/ml in paraffin embedded Human Kidney shows strong nuclear staining in DCT and glomerulus Western Blot: 0.2-0.6ug/ml; ~60kD band observed in Human Ovary lysates (calculated MW of 53.1kD according to NP_006138.1). In transfected HEK293 transiently expressing IRF6 a band of approx. 55kD is observed. This band is not observed in the non-transfected HEK293 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice