I7661-75B

Interferon alpha 2b, Recombinant, Human (IFNa2, IFNa2b), aa24-188

Size

£512.00

SKU:: I7661-75B
Molecular Weight:: 19.4
Purity:: ≥95% (SDS-PAGE). Endotoxin: ≤1EU/ug (LAL)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in PBS, pH 7.4, 10% glycerol
Extra Details:: Interferon induces a variety of effects on target cells including antiviral, antiproliferative, and immunomodulatory activities. Interferon a-2b can either inhibit or enhance immune cell activity within the tightly regulated microenvironment of inflammation, depending upon the concentration of the cytokine and the activation stage of the cell. Interferon a-2 was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Recombinant protein corresponding to aa24-188 of human IFNA2 expressed in E. coli. Uniprot/Accession: NP_000596 Amino Acid Sequence: MCDLPQTHSL GSRRTLMLLA QMRRISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.