Interferon gamma (IFNg)

Size

£409.00

SKU:: I7661-66E
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: E. coli-expressed rat IFNg
Format:: Supplied as a lyophilized powder in 0.09% sodium azide.
Extra Details:: INFg (Interferon-g) is a cytokine that is produced by TH2-like CD4 + T cells. It is engaged in inflammatory response against invading infectious agents. Overreaction to infectious disease and overproduction of INFg could lead to immunopathology, a process very similar to autoimmune response. Therefore, anti-INFg can play a role in limiting the intensity and/or duration of toxic immune response. This is seen as anti-INFg antibodies can interfere with the generation of cytotoxic lymphocytes. In another case, anti-IFNg has also been used to reverse cancer cachexia. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.