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I7661-44B

Integrin beta 6

Size

£825.00

SKU:
I7661-44B
Purity:
Purified by Protein G affinity chromatography from hybridoma culture supernatant.
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Mouse
Immunogen:
Recombinant protein corresponding to Gly22-Asn707 from human Integrin beta 6 expressed in CHO cells.
Clone:
9H134
Format:
Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 200ul sterile PBS.
Extra Details:
Integrin beta 6 (ITGB6) is a 95kD member of the integrin beta family. It forms noncovalent heterodimers with Integrin alpha V and appears on epithelia following injury or inflammation. It activates TGF-beta and assists keratinocyte migration. Human Integrin beta 6 is a type I transmembrane glycoprotein that is 767aa in length. It contains a 688aa extracellular domain (ECD) (aa22-709) that incorporates a 241aa VWF-A domain. Over aa22-707, human Integrin beta 6 ECD shares 90% and 93% aa sequence identity with mouse and pig Integrin beta 6 ECD, respectively. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1ug/ml. Recombinant human Integrin beta 6. Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Conditions:
Blue Ice