I7661-39T
Integrin, beta1 (CD29, Very Late Antigen, VLAb1, Platelet gplla)
Size
£850.00
- SKU:
- I7661-39T
- Purity:
- Purified by Protein A affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Human keratinocytes derived from skin.
- Clone:
- 2Q847 (P5D2)
- Format:
- Supplied as a liquid in 0.02M PBS, pH 7.6, 0.09% sodium azide.
- Extra Details:
- CD29 is the integrin B1 chain which is expressed as heterodimer non-covalently associated with the integrin subunits 1 to 6 (CD49a to CD49f) and known as very late antigens (VLA). It is also called platelet GPlla. It has been reported as receptor of fibronectin. The antigen mediates cellular adhesion primarily to collagen, laminin or fibronectin. It has a broad cellular reactivity but is not expressed by erythrocytes. In normal peripheral blood CD29 blood CD29 is found on approximately 41% of T cells, 40% of CD4+ T lymphocytes, 43% of CD8+ T lymphocytes (1). It is slightly reactive with peripheral B-cells. The co-expression of CD4 and CD29 allows the identification of the helper/inducer subpopulation of CD4 lymphocytes. Applications: Suitable for use in Flow Cytometry, ELISA, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry and Functional blocking. Other applications not tested. Recommended Dilutions: Immunohistochemistry: Acetone fixation, not suitable for paraffin embedded. Immunocytochemistry: Paraformaldehyde fixation at <4% Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice