I7661-16L3

Insulin-like Growth Factor Binding Protein 3 (IGF Binding Protein 3, IGFBP3, IGFBP-3, IBP3, IBP-3, Binding Protein 53, BP-53)

Size

£696.00

SKU:: I7661-16L3
Purity:: Purified by Protein A affinity chromatography
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 162-189 of human FGFR2, UniProt Accession #P17936. Cellular Localization: Secreted. Species Sequence Homology: bovine and porcine
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: IGFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family with an IGFBP domain and a thyroglobulin type-I domain. This protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Applications: Suitable for use in Western Blot and ELISA. Other applications have not been tested. Recommended Dilutions: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.