I7661-09J
Insulin-Like Growth Factor I, Recombinant, Human, aa49-118 (IGF1)
Size
£377.00
- SKU:
- I7661-09J
- Molecular Weight:
- 7.7
- Purity:
- ≥95% (SDS-PAGE). Endotoxin: ≤1EU/ug (LAL)
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Format:
- Supplied as a liquid in PBS, pH 7.4
- Extra Details:
- The Insulin-like growth factor-1 (IGF-1) is mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGF-1 is predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGF-1 belongs to the insulin gene family, which also contains insulin and relaxin. The IGF-1 is similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. This recombinant human IGF-I is globular protein containing 71 amino acids, and 3 intra-molecular disulfide bonds. Recombinant protein corresponding to aa49-118 from human IGF1, expressed in E. coli. Accession: NP_000609.1 Biological Activity: Measured in a cell proliferation assay using MCF-7 human breast cancer cells. The ED50 range is ≤5ng/ml Amino Acid Sequence: MGPETLCGAE LVDALQFVCG DRGFYFNKPT GYGSSSRRAP QTGIVDECCF RSCDLRRLEM YCAPLKPAKS A Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice