I7502-77

ILT7 (Leukocyte Immunoglobulin-like Receptor Subfamily A Member 4, CD85 Antigen-like Family Member G, Immunoglobulin-like Transcript 7, ILT-7, CD85g, LILRA4)

Size

£332.00

SKU:: I7502-77
Application:: Flow Cytometry
Purity:: Purified by affinity chromatography. Endotoxin: <0.1EU/ug (LAL)
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Clone:: 17G10.2
Format:: Supplied as a liquid in PBS, pH 7.2. No preservative added.
Extra Details:: ILT7 (immunoglobulin-like transcript 7) is a member of leukocyte immunoglobulin-like receptor (LIR or LILR) gene family, also known as CD85g and LILRA4. It contains four extracellular Ig domains. In association with FceR1y, ILT7 forms a receptor complex that transduces ITAM-mediated signals. ILT7 is specifically expressed on plasmacytoid dendritic cells (pDCs), but not on myeloid dendritic cells and other peripheral blood leukocytes. ILT7 negatively regulates the innate immune functions of human pDCs. Cross-linking I7502-77 antibody is able to trigger ILT7 mediated signaling. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: ≤0.5ug/10e6 cells in 100ul Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.