I7502-75E

ILT3 (Immunoglobulin-Like Transcript 3, Leukocyte Immunoglobulin-like Receptor Subfamily B Member 4, CD85 Antigen-like Family Member K, ILT-3, Leukocyte Immunoglobulin-like Receptor 5, LIR-5, Monocyte Inhibitory Receptor HM18, CD85k, LILRB4, LIR5)

Size

£351.00

SKU:: I7502-75E
Application:: Flow Cytometry
Purity:: Purified by affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: ILT3 fusion protein
Clone:: ZM4.1
Format:: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Extra Details:: CD85k, known as Immunoglobulin-like transcript (ILT) 3, is an inhibitory receptor expressed by dendritic cells and a subset of white blood cells called monocytes. ILT3, also known as Leukocyte Immunoglobulin-Like Receptor subfamily B member 4 (LILRB4) and Leukocyte Immunoglobulin-like Receptor 5 (LIR-5), is a type I membrane protein that contains cytoplasmic ITIM motifs and is involved in the down-regulation of immune responses. Expression of ILT3 is up-regulated on tolerogenic dendritic cells. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: ≤2ug/10e6 cells in 100ul Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.