I3000-51A
IKK gamma, NT (IKBKG, IkB kinase associated protein 1, NEMO, IkB kinase subunit gamma, AMCBX1, FIP3, Ikbkg, IKKAP1, IKKg, Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase gamma, NF kappa B essential modifier, IP)
Size
£607.00
- SKU:
- I3000-51A
- Application:
- WB
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to amino acids from the N-terminal region of human IKK gamma
- Format:
- Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
- Extra Details:
- Pro-inflammatory cytokines activate the transcription factor NF-kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF-kappa B, at sites that trigger its ubiquitination and degradation. A large, cytokine-responsive Ikappa B kinase (IKK) complex has been purified and the genes encoding 2 of its subunits have been cloned. These subunits, IKK-alpha and Ikk-beta, are protein kinases whose function is needed for NF-kappa B activation by pro-inflammatory stimuli. IKK is composed of similar amounts of IKK-alpha, Ikk-beta, which are differentially processed forms of a third subunit, IKK-gamma. Ikk-gamma interacts preferentially with IKK-beta and is required for the activation of the IKK complex. Aoplications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilutions: Western Blot.: 1:500-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice