13S-Hydroxyoctadecadienoic Acid (13S-HODE)

Size

£397.00

SKU:: H9110-17
Purity:: IgG fraction
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: 13(S)-Hydroxyoctadecadienoic Acid
Format:: Supplied as liquid in PBS.
Extra Details:: 13(S)-HODE (13(S)-hydroxyoctadecadienoic acid) is a 15-lipoxygenase metabolite of linoleic acid produced in endothelial cells, leukocytes, and tumor cells. The biological effects of 13(S)-HODE include inhibition of tumor cell adhesion to the endothelium at concentrations around 1uM (refs 1 and 2) and down regulation of IRGpIIb/IIIa receptor expression (ref 3). 13(S)-HODE methyl ester is a neutral, more lipophilic form of the free acid that can been used as an analytical standard for 13(S)-HODE. Applications: Suitable for use in RIA and Immunohistochemistry. Other applications not tested. Recommended Dilutions: RIA: 2ug/well Optimum dilutions to be determined by researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.