o-Hydroxy Atorvastatin Lactone

Size

£505.00

SKU:: H9036-50
Molecular Weight:: 556.62
Purity:: ~90%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 163217-74-1
Format:: Off-white to pale yellow solid
Extra Details:: A metabolite of Atorvastin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Synonyms: 5-(4-Fluorophenyl)-N-(2-hydroxyphenyl)-2-(1-methylethyl)-4-phenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide; Atorvastatin 2-Hydroxy Lactone CAS No: 163217-74-1 Molecular Formula: C₃₃H₃₃FN₂O₅ Molecular Weight: 556.62 Appearance: Off-white to pale yellow solid Purity: ~90% Melting Point: 96-102°C Method for Determining Identity: Proton NMR (CD3OD) Spectroscopic and Mass Spectrometric Analysis TLC Conditions: SiO2; Dichloromethane: Methanol=9:1; Visualized with UV and AMCS; Rf=0.60. Ethyl Acetate: As Reported Solubility: Chloroform (Slightly), Methanol (Slightly) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.