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H7965-02

Huntingtin Protein (Huntington Disease)

Size

£980.00

SKU:
H7965-02
Purity:
Ascites.
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Mouse
Immunogen:
Huntingtin fragment from aa181-810 as a fusion protein. Species Sequence Homology: human, monkey, mouse and hamster.
Clone:
2Q75
Format:
Supplied as a liquid. No preservative added.
Extra Details:
Huntington's disease (HD) is a neurodegenerative disorder caused by an expanding polyglutamine repeat in the huntingtin gene. HD is a mid-life onset autosomal dominant neurodegeneative disease that is characterized by psychiatric disorders, dementia, and involuntary movements (chorea), leading to death in 10-20 years. Applications: Suitable for use in ELISA, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation and Western Blot. Other applications not tested. Recommended Dilutions: ELISA: 1:500-1:5000 Immunohistochemistry: 1:500-1:5000. Frozen and microwave oven treated paraffin sections (human tissue from previous lot) Immunocytochemistry: 1:500-1:5000 using transfected cells Immunoprecipitation: 1:500-1:5000 Western Blot: 1:1000. Detects huntingtin protein on 10ug of rat brain lysates. Optimal dilutions to be determined by the researcher. Control: Normal human cerebral cortex lysate Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Conditions:
Blue Ice