Hrk (Activator of Apoptosis Harakiri, BH3-interacting Domain Containing Protein 3, BID3, DP5, Harakiri BCL2 Interacting Protein (Contains Only BH3 Domain), Neuronal Death Protein DP5)

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£654.00

SKU:: H7446-50B
Application:: WB
Purity:: Purified by affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 15aa near the center of human HRK (NP_003797).
Format:: Supplied as a liquid in PBS, 0.02% sodium azide.
Extra Details:: HRK regulates apoptosis through its interaction with the anti-apoptotic proteins Bcl-2 and Bcl-XL, and in conjunction to the mitochondrial pore forming protein p32. HRK is thought to have a specific role in initiating neuronal and hematopoietic cell apoptosis, in particular to growth factor deprivation. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 2-5ug/ml. Detects a band at ~13kD in mouse pancreas tissue lysate. Optimal dilutions to be determined by the researcher. Recommended Secondary Antibodies: I1904-40A: IgG, H&L, X-Adsorbed (HRP) Pab Gt xRb I1904-46Q: IgG, H&L (HRP) Pab Gt xRb Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.