H6100-42L

HLA Class 2 Antigen DR (HLA-DR)

Size

£320.00

SKU:: H6100-42L
Purity:: Purified by affinity chromatography
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Human HLA-DR
Clone:: L243
Format:: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide
Extra Details:: This antibody reacts with the HLA-DR antigen, a member of MHC class II molecules. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kD a (heavy) chain and a 27kD B (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. This antibody has been reported to block mixed lymphocyte reactions. Applications: Suitable for use in Flow Cytometry, Western Blot, Immunohistochemistry and Immunoprecipitation. Other applications not tested. Recommended Dilutions: Flow Cytometry: ≤0.5ug/10e6 cells in 100ul or 100ul whole blood Immunohistochemistry: Acetone-fixed, frozen sections Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap