H2030-35A

Herbimycin A (Herbimycin, Antibiotic TAN 420F)

Size

£473.00

SKU:: H2030-35A
Molecular Weight:: 574.7
Purity:: >99% by HPLC
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 70563-58-5
Format:: Supplied as a yellow lyophilized powder.
Extra Details:: Herbimycin A is the major analogue of a complex of benzoquinone ansamycin antibiotics isolated from a Streptomyces hygroscopicus. Herbimycin A inhibits the 90-kD heat-shock protein (Hsp90) which provides essential chaperone support to various signal transduction molecules, including including certain steroid hormone receptors and select kinases. Herbimycin has also been shown to inhibit protein tyrosine kinase and angiogensis. Solubility: Soluble in ethanol, methanol, DMF or DMSO. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with ethanol, methanol, DMF or DMSO.. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Related to: Antibiotic TAN 420C, Antibiotic TAN 420E, Geldanamycin, Herbimycin B