HNF4A, NT (Hepatocyte Nuclear Factor 4-alpha, HNF-4-alpha, Nuclear Receptor Subfamily 2 Group A Member 1, Transcription Factor 14, TCF-14, Transcription Factor HNF-4, HNF4, NR2A1, TCF14)

Size

£645.00

SKU:: H2006-08L
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to RLSKTLVDMDMADY-C from the N-terminal of human HNF4A. Epitope: 2-15
Format:: Supplied as a liquid in TBS, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Extra Details:: The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Western Blot: 0.1-0.5ug/ml Immunohistochemistry (FFPE): 2ug/ml Requires HIER citrate buffer, pH 6.0 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice