H1840-46C

Helicobacter pylori, Cag Antigen

Size

£856.00

SKU:: H1840-46C
Purity:: Purified by Protein G affinity chromatography from ascites
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant fragments of CA-gene of H. pylori.
Clone:: 10J28
Format:: Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
Extra Details:: It is known that H. pylori. strains exhibit a significant degree of diversity. The great variability in the H. pylori. genome may explain why not all infected individuals suffer from ulcer. Some H. pylori. strains contain particular pathogenic genes such as cytokine associated gene A (CagA), while others lack these genes. The CagA protein of H. pylori has been found to be associated with more severe clinical manifestations, such as ulcer disease and gastric cancer. Thus, discrimination between potentially virulent strains may be relevant. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Hybridoma: Sp2/0 myeloma cells with spleen cells from BALB/c mice. Matched Pair: Capture: H1840-46C Detection: H1840-45B Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.