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H1822-90

HAT (Human Airway Trypsin-like Protease, Transmembrane Protease Serine 11D, TMPRSSIID)

Size

£832.00

SKU:
H1822-90
Purity:
Purified by Protein G affinity chromatography from cell culture supernatant.
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Mouse
Immunogen:
Recombinant protein corresponding to Ala42-Ile418 of human HAT, expressed in NS0 cells. Species Sequence Homology: chimpanzee, 99%; canine, 79%; rat and mouse, 67%. Epitope: catalytic-domain of rhHAT.
Clone:
7H93
Format:
Supplied as a lyophilized powder PBS, pH 7.4, 5% trehalose. Reconstitute with 200ul sterile PBS.
Extra Details:
Human Airway Trypsin-like protease (HAT), also known as Transmembrane Protease, Serine 11D (TMPRSSIID), is a type II transmembrane serine protease that is expressed in the cells of the submucosal serous glands of the bronchi and trachea. The deduced sequence predicts a short cytoplasmic tail (aa1-20), a transmembrane domain (aa21-41), and an ectodomain consisting of a SEA domain (aa44-164) and a catalytic domain (aa187-418). The single-chain precursor can be converted into a disulfide-linked two-chains, one of which corresponds to the catalytic domain. Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilutions: Western Blot: 1ug/ml with recombinant human Airway Trypsin-like Protease/HAT Optimal dilutions should be determined by researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Conditions:
Blue Ice