G8957-01P

Granzyme B, NT (GRB, GZMB, C11, Cathespin G-like 1, CCPI, CGL1, CGL-1, CSPB, CSP-B, CTLA1, CTLA-1, CTSGL1, Cytotoxic T Lymphocyte-associated Serine Esterase 1, Cytotoxic T Lymphocyte Proteinase 2, Fragmentin 2, Fragmentin-2, Granzyme 2, Human Lymphocyte Protein, HLP, Lymphocyte Protease, Protease Serine B, SECT, T-cell Serine Protease 1-3E)

Size

£767.00

SKU:: G8957-01P
Application:: IHC-Fr
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Synthetic peptide corresponding to human Granzyme B at N-terminal.
Format:: Supplied as a liquid in 10mM PBS, pH 7.4, BSA, sodium azide.
Extra Details:: Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin-fixed, paraffin-embedded): 1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.