Golgi Associated, Gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3, ARF binding protein 3, HGNC:17079, KIAA0154, ADP-ribosylation factor binding protein 3, Golgi-localized, gamma ear-containing, ARF-binding protein 3)

Size

£806.00

SKU:: G8576-88C
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Recombinant human Syntabulin, aa489-656 (E. coli).
Format:: Supplied as a lyophilized powder in 0.2um sterile-filtered solution in PBS, 5% trehalose. Reconstitute with 40-50% glycerol, PBS.
Extra Details:: Syntabulin (also Golgi-localized synaphilin-related protein) is a 75kD molecule that belongs to the syntaxin-binding and kinesin-1 family of motor adaptor proteins. It is highly spliced, with various forms associated with different tissues. In neurons, it anchors syntaxin-1 to KIF5B, creating a complex by which synaptic components can be transported to synaptic terminals. Human Syntabulin is a type II transmembrane (TM) protein 663aa in length. It contains one coiled-coil region (aa271-353) and a TM domain between aa 606-626. Alternate splice forms show alternate start sites at Met120 and Met207, a five aa substitution for aa1-8, a 16aa insertion after Lys8, and an eight aa substitution for aa1-76. Over aa486-653, human Syntabulin shares 83% aa identity with mouse Syntabulin. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 0.5-1.0ug/ml Western Blot: 1.0ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice