G8177-14

CD235a (Glycophorin-A, GPA, GYPA, GPSAT, MN, MNS, MN Sialoglycoprotein, PAS-2, Sialoglycoprotein alpha/beta)

Size

£601.00

SKU:: G8177-14
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Synthetic peptide corresponding to human CD235a at N-terminal.
Clone:: HIR2
Format:: Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
Extra Details:: CD235a (glycophorin A, GPA) is a transmembrane sialoglycoprotein expressed on erythrocytes and their precursors. Similarly to CD235b (glycophorin B, GPB), these molecules provide the cells with a large mucin-like surface, which minimalizes aggregation between erythrocytes in the circulation. GPA is the carrier of blood group M and N specificities, while GPB accounts for S, s and U specificities. CD235a is a receptor of Hsa, a Streptococcus adhesin. Applications: Suitable for use in Flow Cytometry, Agglutination Analysis and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 1-4ug/ml Immunohistochemistry: frozen and paraffin Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.