G3900-24G
GLUT 3 (Glucose Transporter)
Size
£754.00
- SKU:
- G3900-24G
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to 13aa sequence from human GLUT 3. Epitope: ~N-terminus, Extracellular domain
- Format:
- Supplied as a liquid in PBS, pH 7.2, 0.1% BSA.
- Extra Details:
- Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters. Molecular cloning of these glucose transporters has identified a family of closely related genes that encodes at least 7 proteins (Glut-1 to Glut-7, Mol. Wt. 40-60kD) and Sodium glucose co-transporter-1 (SGLT-1, 662 amino acids; ~75kD). Individual member of this family have identical predicted secondary structures with 12 transmembrane domains. Both N and c-termini are predicted to be cytoplasmic. Most differences in sequence homology exist within the four hydrophilic domains that may play a role in tissue-specific targeting. Glut isoform differ in their tissue expression, substrate specificity and kinetic characteristics. Applications: Suitable for use in ELISA and Immunohistochemistry. Western Blot, though not tested, may potentially be used as an application. Other applications not tested. Recommended Dilutions: ELISA: 0.5-1ug/ml; Control peptide can be used to coat ELISA plates at 1ug/ml. Immunohistochemistry: 2-20ug/ml Optimal dilutions to be determined by the researcher. Control Peptide: G3900-24H: GLUT 3, Human, Control Peptide (Glucose Transporter) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice