G3009-02

Germinal Center Kinase (GC Kinase, GCK, B Lymphocyte Serine/threonine-protein Kinase, BL44, Mitogen-activated Protein Kinase Kinase Kinase Kinase 2, MAP4K2, MAPK/ERK Kinase Kinase Kinase 2, MEK Kinase Kinase 2, MEKKK 2, Rab8-interacting Protein, RAB8IP)

Size

£696.00

SKU:: G3009-02
Purity:: Purified by ammonium sulfate precipitation
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide selected from the center region of human MAP4K2 (KLH).
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-1:500 Immunohistochemistry: 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.