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G2040-02C

Glucagon, Recombinant, Human, aa90-180, His-Tag (GCG, Glicentin-related Polypeptide, GRPP)

Size

£512.00

SKU:
G2040-02C
Molecular Weight:
12.8
Purity:
≥95% (SDS-PAGE)
Storage Conditions:
-20°C
Supplier:
United States Biological
Format:
Supplied as a liquid in 20mM Tris-HCl buffer, pH 8, 1mM DTT, 0.2M sodium chloride, 50% glycerol.
Extra Details:
Glucagon, also known as GCG, a hormone secreted by the pancreas, raises blood glucose levels. Its effect is opposite that of insulin, which lowers blood glucose levels. The pancreas releases glucagon when blood sugar (glucose) levels fall too low. Glucagon causes the liver to convert stored glycogen into glucose, which is released into the bloodstream. Glucagon also stimulates the release of insulin, so glucose can be taken up and used by insulin-dependent tissues. Thus, glucagon and insulin are part of a feedback system that keeps blood glucose levels at a stable level. Purified by using conventional chromatography techniques. Source: Recombinant corresponding to aa90-180 of human GCG, fused to His-tag at N-terminal, expressed in E.coli. Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MKRHDEFERH AEGTFTSDVS SYLEGQAAKE FIAWLVKGRG RRDFPEEVAI VEELGRRHAD GSFSDEMNTI LDNLAARDFI NWLIQTKITD RK Molecular Weight: ~12.8kD (112aa), confirmed by MALDI-TOF Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Conditions:
Blue Ice