G2035-APC

GFRa2 (GFRalpha2, Neurturin Receptor) (APC)

Size

£971.00

SKU:: G2035-APC
Application:: WB
Purity:: Purified by Ion Exchange chromatography.
Storage Conditions:: 4°C Do Not Freeze
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to the C-terminus of human GFRa2.
Format:: Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Extra Details:: Neurturin is a member of the GDNF family and has an important role in the control of vertebrate neuron survival and differentiation. GFRa2 is a receptor for neurturin. It mediates the NRTN-induced autophosphorylation and activation of the RET receptor. It is also able to mediate GDNF signaling through the RET tyrosine kinase receptor. GRFa2 is a 52kD glycoprotein and is a GPI-linked cell surface receptor. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.