G2034-45

Gilvocarcin M (Anandimycin B, Toromycin B, Antibiotic 1072A)

Size

£473.00

SKU:: G2034-45
Molecular Weight:: 482.5
Purity:: > 95% by HPLC
Storage Conditions:: -20°C, protect from light
Supplier:: United States Biological
CAS Number:: 77879-89-1
Extra Details:: Gilvocarcin M is the minor analogue of a complex of C-glycoside antitumor actives isolated from a Streptomyces sp.. Gilvocarcin M contains a methyl group in the 8-position and is less active than the vinyl analogue (gilvocarcin V), which is thought to act as an inhibitor of human topoisomerase II. Gilvocarcin M displays potent antibacterial, antifungal, antiviral and antitumor activity. Recent research on the gilvocarcins suggests that they act as photoactivated crosslinkers of DNA to histones. Purity: > 95% by HPLC Solubility: Soluble in DMF or DMSO. Moderately soluble in methanol or ethanol. Related to: Chrysomycin A, Chrysomycin B, Gilvocarcin V, O-Deacetyl-ravidomycin