GFR alpha 2 (GDNF family receptor alpha-2, GFR-alpha-2, Neurturin receptor alpha, NTNR-alpha, NRTNR-alpha, TGF-beta-related neurotrophic factor receptor 2, GDNF receptor beta, GDNFR-beta, RET ligand 2) (Not for Export EU)

Size

£735.00

SKU:: G2033-31
Purity:: Serum
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: A synthetic peptide (PRVEKTPSLPDDLSD) as a part of human GFR alpha-2 protein (aa: 376-390) conjugated to KLH.
Format:: Supplied as a lyophilized powder. Reconstitute in 100ul of sterile water. Centrifuge to remove any insoluble material.
Extra Details:: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. Cellular Localization: Cell membrane; lipid-anchor; GPI-anchor (By similarity). Alternative Products: 2 named isoforms produced by alternative splicing. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.