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G2024-53J2-APC

Gelsolin (GSN, Actin Depolymerizing Factor, ADF, AGEL, Amyloidosis Finnish Type, Brevin, DKFZp313L0718) (Azide Free) (APC)

Size

£927.00

SKU:
G2024-53J2-APC
Purity:
Purified by ammonium sulfate precipitation.
Storage Conditions:
4°C Do Not Freeze
Supplier:
United States Biological
Host:
Mouse
Immunogen:
Partial recombinant protein corresponding to a portion of amino acids within aa673-783 of human Gelsolin with a GST tag. MW of GST tag alone is ~26kD.
Clone:
3G5
Format:
Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Extra Details:
The protein encoded by this gene binds to the plus ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. Applications: Suitable for use in FLISA, Immunohistochemistry and Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1:500-1:1000 Immunohistochemistry (Paraffin): 1.5ug/ml FLISA: 3ng/ml-1ug/ml Optimal dilutions to be determined by the researcher. Hybridoma: Sp2/0 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
Shipping Conditions:
Blue Ice