G2023-55A
GCP 2 (Chemokine (CXC motif) ligand 6, Chemokine alpha 3, CKA3, CXCL6, Granulocyte chemotactic protein 2, SCYB6, Small inducible cytokine subfamily B (Cys X Cys) member 6) (Biotin)
Size
£479.00
- SKU:
- G2023-55A
- Purity:
- Purified by antigen affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Highly purified, recombinant GCP-2
- Format:
- Supplied as a lyophilized powder from a sterile-filtered solution in PBS, pH 7.4. Labeled with Biotin.
- Extra Details:
- Human GCP-2 is an 8kD protein containing 73 amino acid residues. Neutrophil recruitment to inflammatory sites is mediated by two related receptors: CXCR1 and CXCR2. Both receptors share two ligands, interleukin-8 (CXCL8) and GCP2 (CXCL6). GCP2 belongs to the intercrine alpha (chemokine CxC) family. GCP-2 promotes neutrophil chemotaxis and degranulation. Application: Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of hGCP-2 (100.0 ng/ml), a concentration of 2.0–5.0 ug/ml of this antibody is required. ELISA: To detect hGCP-2 by direct ELISA (using 100µl/well antibody solution) a concentration of at least 0.5ug/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of 0.2–0.4 ng/well of recombinant hGCP-2. Western Blot: To detect hGCP-2 by Western Blot analysis this antibody can be used at a concentration of 0.1–0.2 ug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hGCP-2 is 1.5–3.0 ng/lane, under either reducing or non-reducing conditions. Usage: For research use only. Reconstitution: The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at- 20°C. When reconstituted in sterile water to a concentration of ≥ 0.2 mg/ml the antibody is stable for at least six weeks at 2-4°C. Country of Origin: USA
- Shipping Conditions:
- Blue Ice