G1044-62
Galiellalactone
Size
£576.00
- SKU:
- G1044-62
- Molecular Weight:
- 194.2
- Purity:
- ≥90% by HPLC
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- CAS Number:
- 133613-71-5
- Format:
- Supplied as a white to light tan powder
- Extra Details:
- Galiellalactone was originally isolated from Galiella rufa as a plant growth regulator. Recently it was shown to inhibit IL-6 induced SEAP expression with IC50 values of 250-500nM by blocking the binding of the activated Stat3 dimers to their DNA binding sites without inhibiting the tyrosine and serine phosphorylation of the Stat3 transcription factor. Solubility: Soluble in ethanol, methanol, DMF or DMSO. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with ethanol, methanol, DMF or DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice