Frizzled 8 (Frizzled Family Receptor 8, Frizzled-8, Fz-8, FZD8, hFz8)

Size

£642.00

SKU:: F6401-38H
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to C-SYPKQMPLSQV, from human FZD8, at C-terminal (NP_114072.1).
Format:: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Extra Details:: FZD8 is a Frizzled Receptor that mediates Wnt signaling and is involved in determining vertebrate axis and tissue polarity. FZD8 is expressed during embryonic development in forming and differentiating somites in mice. FZD8 expression has been reported in brain, heart, kidney, pancreas, and skeletal muscle. ESTs have been isolated from embryo, eye, head/neck, heart, kidney, liver/spleen, pancreas, prostate, and testis libraries, as well as many tumor libraries. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Western Blot: 1-3ug/ml, observed in human heart pancreas lysates on ~75kD bands Immunohistochemistry (Paraffin): 3ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.