F6401-30A1
Frizzled 7 (Frizzled-7, Frizzled (Drosophila) Homolog of 7, Frizzled Homolog 7, Fz 7, Fz-7, FZD7, FzE3, hFz7, Homolog of Drosophila Frizzled 7) (BSA Free)
Size
£767.00
- SKU:
- F6401-30A1
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Goat
- Immunogen:
- Synthetic peptide corresponding to C-RFYHRLSHSSKGET from the C Terminus of human Frizzled 7. Species Sequence Homology: mouse
- Format:
- Supplied as a liquid in PBS, 0.02% sodium azide. BSA free.
- Extra Details:
- Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. Applications: Suitable for use in Peptide ELISA, Immunohistochemistry and Western Blot. Other applications not tested. Recommended Dilutions: Peptide ELISA: 1:64,000. Western Blot: 0.3-1ug/ml; ~60kD band observed in lysates of cell lines HEK293 and HepG2 (calculated MW of 63.6kD according to NP_003498). Immunohistochemistry (Formalin-fixed, paraffin-embedded): 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice