F6010-10A1
Formyl Peptide Receptor-like 1, Control Peptide
Size
£512.00
- SKU:
- F6010-10A1
- Purity:
- 95+% HPLC, Mass Spec
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide (ASWGGTPEERLKC) corresponding to residues of the 2nd extracellular loop of human FPRL1, conjugated to KLH.
- Format:
- Supplied as a white to off-white lyophilized powder.
- Extra Details:
- FPRL1 is a low affinity receptor to N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). FPRL1 has been reported in phagocytes, monocytes, neutrophils, differentiated myeloid cells from bone marrow, granulocyte HL-60 cells, and synovial fibroblasts. ESTs have been isolated from blood, leukocyte, lung, and placenta libraries. Sequence: The sequence ASWGGTPEERLKC corresponds to amino acids 181-192 of FPRL1, plus one added Cysteine residue. Applications: Control Peptide for anti-FPRL1, Cat#F6010-10A Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice