F4305-08
Fibroblast Growth Factor Receptor beta (Flg, FGFRb, FGFR1)
Size
£800.00
- SKU:
- F4305-08
- Purity:
- Purified by affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Bovine Fibroblast Growth Factor Receptor beta purified from Coronary Venular Endothelial Cells (CVEC).
- Clone:
- 3G150
- Format:
- Supplied as a liquid in PBS, 0.09% sodium azide.
- Extra Details:
- Currently four FGF receptors have been identified, FGFR-1 (flg), FGFR-2 (bek), FGFR-3, and FGFR-4. FGFR-1 and FGFR-2 exist in multiple forms that represent alternative splicing of their respective genes. The FGF Receptor consists of three immunoglobulin-like domains, a transmembrane region and a cytosolic tyrosine kinase domain which is activated by ligand binding. FGFs play important roles in angiogenesis, wound healing, tumorigenesis and metastasis. The FGF family consists of 7 members, FGF-1 through FGF-7. FGFs 1 and 2 are also known as basic FGF (bFGF) and acidic FGF (aFGF), respectively. It is known that multiple FGFs can bind and activate FGFR-1, FGFR-2, and FGFR-3. Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation, Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilutions: ELISA: 0.1-1ug/ml Western Blot: 2ug/ml Immunoprecipitation: 2-5ug Immunohistochemistry (Paraffin): 1:20-1:200 Optimal dilutions to be determined by the researcher. Hybridoma: Sp2/0/Ag14 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice