F0019-75H
Fatty Acid Binding Protein, Heart (FABP)
Size
£819.00
- SKU:
- F0019-75H
- Purity:
- Purified by Protein G affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Purified human Fatty Acid Binding Protein, Heart (FABP)
- Clone:
- 6A546 (66E2)
- Format:
- Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide. Also available without BSA and azide, see F0019-75H1
- Extra Details:
- The human Fatty Acid Binding Protein is derived from the human FABP3 gene. FABPs are small intracellular proteins (~13-14kD) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. H-FABP is localized in the heart, skeletal and smooth muscle, mammary epithelial cells, aorta, distal tubules of the kidney, lung, brain, placenta, and ovary. It is also useful as marker for brain damage. Applications: Suitable for use in ELISA, Immunoprecipitation, Western Blot and Purification. Other applications not tested. Recommended Dilutions: Western Blot: 1:50 using reduced conditions. Detected a band of ~15kD. Optimal dilutions to be determined by the researcher. Positive Control: Heart cells, recombinant human FABP Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice