Fas IgG1 Fc & Hinge Region, Fusion Protein (CD95, APO-1)

Size

£735.00

SKU:: F0019-61M
Molecular Weight:: 44.3
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: 4°C Do Not Freeze
Supplier:: United States Biological
Format:: Supplied as a liquid in FBS, 50mM Sodium Phosphate pH 7.5, 100 M Potassium Chloride, 150mM NaCl, 0.5mg/ml Gentamicin Sulfate.
Extra Details:: Human CD95 (APO-1/FAS) is a type I cell surface glycoprotein that is strongly upregulated on activated T cells, B cells, NK cells and thymocytes (1). CD95 plays an important role in programmed cell death or apoptosis (2). Apoptosis appears to be a mechanism for regulating the immune response (3, 4). CD95-huIg fusion protein blocks binding of anti-human CD95 antibody to cells expressing CD95. Transfectant Cell Line: CHO Functional Application: CD95-huIg fusion protein inhibits CD95 ligand mediated apoptosis of Jurkat cells. Human CD95 (APO-1/FAS)huIg Fusion Protein* Molecular Structure: A soluble fusion protein consisting of the extracellular (175aa) domain of human CD95 fused to human IgG1 Fc (234aa). Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.