Fanconi anemia G (Fanconi anemia Group G-Protein, Protein FACG, DNA-repair protein XRCC9)

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£594.00

SKU:: F0019-58W8
Application:: WB
Purity:: Whole antisera
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: A C-Terminal peptide within residues 550- 622 of 622. Homology: 100% homology with human protein. 88% homology with mouse protein.
Format:: As reported
Extra Details:: FANCG, involved in Fanconi anemia, confers resistance to both hygromycin and mitomycin C. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies. A minimum of 8 FA genes have been identified. Cellular Localization: The major form is nuclear. The minor form is cytoplasmic. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.