Factor VIIa

Size

£531.00

SKU:: F0015-13
Purity:: ~95% by SDS-PAGE
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Purified human factor VIIa
Format:: Supplied as a liquid, ddH2O, 50% glycerol.
Extra Details:: Human coagulation factor VII is a single chain protease that circulates in the blood as a weakly active zymogen at concentrations of approximately 10nmol/L. When converted to the active 2 chain form (VIIa), it is a powerful initiator of hemostasis. Recombinant Factor VIIa is a unique hemostatic agent with potential for broad-spectrum applications in bleeding patients with congenital and acquired bleeding abnormalities. At present, recombinant Factor VIIa is only approved for the treatment of hemophilia A and B patients who have acquired antibodies to Factors VIII and IX. Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilutions: ELISA: 10ug/ml Western Blot: 10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.