E8949-54
Eukaryotic Translation Initiation Factor 4G (eIF4G)
Size
£626.00
- SKU:
- E8949-54
- Purity:
- Purified
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to the sequence around Gly188 of human eIF4G.
- Clone:
- 7H21(C45A4)
- Format:
- Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 0.02% sodium azide, 50% glycerol.
- Extra Details:
- The initiation of translation is an important biological event, and a variety of factors contribute to this process. The eIF4 family of translation initiation factors bind to the 5' m7GTP mRNA cap and function to unwind the secondary structure of mRNA (1, 2). The amino-terminal portion of eIF4G physically associates with eIF4E and stimulates the binding of eIF4E to the mRNA cap structure (3). eIF4G also interacts with eIF3 and eIF4A (4), serving as an adaptor molecule in the eIF4 complex. Moreover, eIF4G also plays a role in internal ribosomal entry site (IRES)-mediated initiation of translation (5,6). Applications: Suitable for use in Immunofluorescence, Flow Cytometry, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice