E3451-26H

ErbB2 (Receptor Tyrosine-protein Kinase erbB-2, p185erbB2, Proto-oncogene C-erbB-2, Proto-oncogene NEU, Tyrosine Kinase-type Cell Surface Receptor HER2, Metastatic Lymph Node Gene 19 Protein MLN 19, HER2, NEU, NGL)

Size

£696.00

SKU:: E3451-26H
Purity:: Purified by ammonium sulfate precipitation.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Human recombinant HER2 protein.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues. Applications: Suitable for use in ELISA, Western Blot, Indirect Flow Cytometry, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Immunohistochemistry: 1:10-1:50 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.