E3428-74
Epothilone A
Size
£464.00
- SKU:
- E3428-74
- Molecular Weight:
- 493.7
- Purity:
- ~98% (HPLC)
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- CAS Number:
- 152044-53-6
- Format:
- Supplied as a white to off-white powder.
- Extra Details:
- Epothilone A is a microtubule inhibitor isolated from the myxobacteria, Sorangium cellulosum. Epothilone A acts by stabilising microtubule formation at the taxol binding site and causes cell cycle arrest at the G2/M transition, leading to cytotoxicity. Epothilone A is under investigation as an antitumor agent. Source: Epothilone A from Sorangium cellulosum. Molecular Weight: ~493.7 Solubility: Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice