E3317-75
Enzastaurin, Free Base
Size
£209.00
- SKU:
- E3317-75
- Molecular Weight:
- 515.6
- Purity:
- ~99%
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- CAS Number:
- 170364-57-5
- Format:
- Supplied as a red-orange powder.
- Extra Details:
- Enzastaurin inhibits PKCb, PKCa, PKCy and PKCe with IC50's of 0.006, 0.039, 0.083 and 0.110uM, respectively. Enzastaurin apparently inhibits tumor growth via multiple mechanisms: suppression of tumor cell proliferation, induction of tumor cell apoptosis and inhibition of tumor-induced angiogenesis. Solubility: Soluble in DMSO at 7.1mg/ml with warming; very poorly soluble in ethanol; very poorly soluble in water; maximum solubility in plain water is estimated to be about 1-10uM; buffers, serum, or other additives may increase or decrease the aqueous solubility. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Blue Ice