E2291-53B

Endoplasmic Reticulum-associated Amyloid Beta-peptide binding protein (ERAB)

Size

£812.00

SKU:: E2291-53B
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide (DLPNSGGEAQAKKLGNN) corresponding to aa41-57 of human ERAB
Format:: Supplied as a liquid in PBS, pH 7.2.
Extra Details:: Endoplasmic reticulum-associated amyloid beta-peptide binding protein (ERAB) is a 27kD protein, member of the short-chain dehydrogenase/reductase family, it catalyses the oxidation of a wide variety of fatty acids, alcohols, and steroids. It is constitutively expressed in tissues and overexpressed in neurons affeceted in Alzheimer's disease. ERAB binds amyloid.beta and may be a determining factor in the level of cytotoxicity observed in the brain of Alzheimer's patients. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1000 Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.