E2286-19

Endogenous Retrovirus Type K, gag protein (HERV K)

Size

£745.00

SKU:: E2286-19
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: HERV K gag antigen (82kD).
Clone:: 5i76 (4D4/F7)
Format:: Supplied as a liquid in PBS, pH 7.4.
Extra Details:: Endogenous retroviruses contribute to the evolution of the host genome and can be associated with diseases in their hosts. Human endogenous retrovirus K (HERV-K) is related to mouse mammary tumor virus (MMTV) and is present in the genomes of catarrhines (humans, apes, and cercopithecoids (old world monkeys)). All humans have about 30 to 50 HERV-K proviruses in their germline DNA. Expression of HERV-K genes has been reported in several tissues including male germ cell tumors and normal placenta where budding viral particles can be detected. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilutions: ELISA: 1:2000 Western Blot: 1:8000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.