E0254-75A

EBF3 (Transcription Factor COE3, Early B Cell Factor 3, EBF-3, Olf-1/EBF-like 2, O/E-2, OE-2, COE3)

Size

£685.00

SKU:: E0254-75A
Purity:: Purified.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: EBF3 (NP_001005463, 381-481aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Clone:: 8D6
Format:: Supplied as a liquid in PBS, pH 7.2.
Extra Details:: EBF3 (Early B-cell factor 3) belongs to the conserved Olf/EBF family of helix-loop-helix transcription factors, which regulate neurogenesis and differentiation. It recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. EBF3 is expressed in normal brain but is silenced in brain tumors suggesting that it may regulate a transcriptional program underlying a putative tumor suppression pathway. Applications: Suitable for use in ELISA, Immunohistochemistry (paraffin), and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.