D9300-30A

DR4 (Death Receptor 4, Apo2, CD261, CD261 Antigen, Cytotoxic Ligand TRAIL Receptor, Cytotoxic TRAIL Receptor, MGC9365, T10A, TNF Related Apoptosis Inducing Ligand Receptor 1, TRAIL Receptor 1, TRAIL R1, TRAILR1, TRAIL-R1, TRAILR-1, Tumor Necrosis Factor Receptor Superfamily Member 10a, TNFRSF10A) (APC)

Size

£850.00

SKU:: D9300-30A
Application:: Flow Cytometry
Purity:: Purified by Protein G affinity chromatography from hybridoma culture supernatant.
Storage Conditions:: 4°C Do Not Freeze
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant corresponding to Ala24-Asn239 from human TRAIL R1 expressed in Sf21 cells.
Clone:: 11D73
Format:: Supplied as a liquid in PBS in BSA, 0.09% sodium azide. Labeled with Allophycocyanin (APC).
Extra Details:: TNF-Related Apoptosis-Inducing Ligand receptor 1(TRAIL R1), also known as DR4 (Death Receptor 4), is a type I transmembrane protein that belongs to the TNF receptor family and is designated TNFRSF10A. It is expressed on a wide variety of tissues. Binding of the ligand TRAIL (TNFSF10) induces oligomerization of TRAIL R1 and signal transduction through its death domain leading to apoptosis of the target cell. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.