D9300-03B

DR3 (Death Receptor 3, DDR3, APO3, Apo-3, Apoptosis-inducing Receptor AIR, Apoptosis-mediating Receptor DR3, Apoptosis-mediating Receptor TRAMP, Lymphocyte-associated Receptor of Death, LARD, Protein WSL, Protein WSL-1, TNFRSF12, TR3, TRAMP, Tumor Necrosis Factor Receptor Superfamily Member 25, TNFRSF25, UNQ455/PRO779, WSL, WSL1, WSL-1, WSL-LR) (Biotin)

Size

£639.00

SKU:: D9300-03B
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant corresponding to human HPB-MLT cells CD278(ICOS) -muIg
Clone:: 11K6
Format:: Supplied as a liquid in 50mM sodium phosphate, pH 7.5, 100mM potassium chloride, 150mM sodium chloride, 0.2% BSA, 0.04% sodium azide, 5% glycerol. Labeled with Biotin.
Extra Details:: Human DR3 (TRAMP, LARD) was designated TNF receptor superfamily member 25. TL1A is a ligand which can induce apoptosis through a cytoplasmic death domain similar to the CD178-CD95 (FasL-Fas) interaction. Alternatively, engagement of DR3 on T cells can synergize with other activating signals to enhance IFN gamma production. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.