D9016-40
Dopamine Receptor, D2R (Not for Export EU)
Size
£505.00
- SKU:
- D9016-40
- Purity:
- Serum
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to 11aa near the N-terminus, extracellular doman 1 ligand of rat D2R, conjugated to KLH. Species Sequence Homology: mouse; 100%, human and bovine; 90%, canine; 72%.
- Format:
- Supplied as a liquid in PBS, 0.09% sodum azide
- Extra Details:
- Dopamine is an endogenous catecholamine that influences many cellular activities, including behavior, hormone synthesis and release, blood pressure and intracellular ion transport. A family of 5 Dopamine Receptors (DR) genes, D1-D5, have been identified based upon the amino acid identity, pharmacological specificity and effector responses. DR have been classified into either the D1-like (D1, D1B, and D5) or D2-like (D2, D3, and D4). Dopamine D2 receptor is known to exist in the short (D2S) and the long (D2L)forms that are encoded by splice variants of a single gene and differ only by the presence of an additional 29 amino acid in the intracellular, cytoplasmic loop 3. D2L receptor is a 446aa, G- protein coupled, and transmembrane receptor protein. D2R may play a role in the coupling of the receptor to G-proteins. All members of this family have similar structure and contain 7 putative transmembrane domains. Applications: Suitable for use in ELISA. Western Blot, though not tested, may potentially be used as an application. Other applications not tested. Recommended Dilutions: ELISA: 1:10,000-1:50,000 Control peptide can be used to coat ELISA plates at 1ug/ml and detected with antibodies Optimal dilutions to be determined by the researcher. Control Peptide: D9016-42: Dopamine Receptor, Rat, Control Peptide, D2R Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice